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吴刚

时间:2020-11-09

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个人简介

吴刚,男,博士,教授,硕士生导师和博士生导师。

 

联系方式

办公电话:0571-63741826电子邮箱:wugang @ zafu.edu.cn

 

教育经历

2000年获浙江大学生物物理学博士学位,2000-2002年在北京大学蛋白质工程与植物基因工程国家重点实验室从事博士后研究,2002-2012年在美国宾夕法尼亚大学生物系从事博士后研究,任研究科学家,从事植物遗传发育调控机制的研究。在《Cell》、《PNAS》等杂志上发表论文多篇。负责组建全新的植物分子遗传与发育实验室。自实验室组建以来,先后获国家自然科学基金9项、省杰出青年基金1项,浙江省自然科学基金2项,总经费达600余万元。实验室主要从事植物童期调控的分子机制研究。近年来,已经在《Plant Cell》、《Plant Physiology》、《Journal of Experimental Botany》、《Genetics》等国际知名期刊上发表论文多篇。2018年出任浙江农林大学农业与食品科学学院院长。

 

近年承担主要科研项目

1、国家自然科学基金项目谷氨酰胺合成酶调控拟南芥幼年向成年阶段转变的分子机制研究2018-2021),60万,主持。

2、国家自然科学基金项目miRNA 网络系统调控拟南芥幼年向成年转变的分子机制2014-2016),30万,主持。

3、浙江省杰出青年基金项目调控微小 RNA miR156 表达的分子机理研究2013-201630万,主持。

4、国家自然科学基金项目拟南芥幼年向成年转变的分子机制2013-201675万,主持。


近年发表的主要论文(*通讯作者):

1.Changkui Guo, Yunmin Xu, Min Shi,Yongmin Lai, Xi Wu, Zhujun Zhu, Huasen Wang, R Scott Poethig*, and Gang Wu* (2017) Repression of miR156 by miR159 regulates the timing of the juvenile-to-adult transition in Arabidopsis. Plant Cell, 29: 1293-1304.

2.Yunmin Xu, Changkui Guo, Bingying Zhou, Chenlong Li, Huasen Wang, Ben Zheng, Han Ding, Zhujun Zhu, Angela Peragine, Yuhai Cui, Scott Poethig, and Gang Wu* (2016) Regulation of vegetative phase change by SWI2/SNF2 chromatin remodeling ATPase BRAHMA. Plant Physiology, 1722416-2428.

3.Mingli Xu, Tieqiang Hu, Jianfei Zhao, MeeYeon Park, Keith Earley, Gang Wu, Li Yang, R. Scott Poethig (2016) Developmental Functions of miR156-Regulated SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) Genes in Arabidopsis thaliana. PLOS Genetics, DOI:10.1371/journal.pgen.1006263.

4.Shengjun Feng, Yunmin Xu, Changkui Guo, Jirong Zheng, Bingying Zhou, Yuting Zhang, Yue Ding, Lu Zhang, Zhujun Zhu, Huasen Wang, and Gang Wu* (2016) Modulation of miR156 to identify traits associated with vegetative phase change in tobacco (Nicotiana tabacum L.). Journal of Experimental Botany, doi:10.1093/jxb/erv551.

5.Gang Wu, Gabrielle Rossidivito, Tieqiang Hu, Yosef Berlyandand R. Scott Poethig (2015) Traffic Lines: New Tools for Genetic Analysis in Arabidopsis thaliana. Genetics, 200:35-45.

6.Gang Wu* (2013) Plant MicroRNAs and Development. Journal of Genetics and Genomics, 40:217-230.

7.Li Yang, Gang Wu, R. Scott Poethig (2012) Mutations in the GW-protein SUO reveal a developmental function for miRNA-mediated translational repression in Arabidopsis. PNAS, 109: 315-320.

8.Gang Wu, Mee Yeon Park, Susan Conway, Jia-wei Wang, Detlef Weigel, and R. Scott Poethig (2009) The sequential action of miR156 and miR172 regulates developmental timing in Arabidopsis. Cell 138 (4): 750-759.

9.Gang Wu, Wan-ching Lin, Tengbo Huang, R. Scott Poethig, Patricia S. Springer, Randall A. Kerstetter (2008) KANADI1 regulates abaxial-abaxial polarity in Arabidopsis by directly repressing the transcription of ASYMMETRIC LEAVES2. PNAS 105(42): 16393-16398.

10.Gang Wu and R. Scott. Poethig (2006) Temporal regulation of shoot development in Arabidopsis by miR156 and its target SPL3. Development 133: 3539-3547.

11.Gang Wu, Hairui Cui, Gongyin Ye, Yingwu Xia, Sardana Ravinder, Xiongying Cheng, Yi Li, Altosaar Illimar & Qingyao Shu (2002) Inheritance and expression of the cry1Ab gene in Bt (Bacillus thuringiensis) transgenic rice. Theoretical and Applied Genetics 104(4): 727-734.

12.Meeyeon Park, Gang Wu, Alfredo Gonzalez-Sulser, Herve Vaucheret, and R. Scott Poethig (2005) Nuclear processing and export of microRNAs in Arabidopsis. PNAS, 102(9): 3691-3696.

13.Feng Zhou, Gang Wu, Wulan Deng, Yingying Pu, Chunhong Wei, Yi Li (2007) Interaction of rice dwarf virus outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8. FEBS Letters 581: 34-40.

14.Angela Peragine, Manabu Yoshikawa, Gang Wu, Heidi L. Albrecht, R. Scott Poethig (2004) SGS3 and SGS2/SD1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis. Genes & Development 18:2368-2379.

15.Michael Smith, Matthew Willmann, Gang Wu, Barbara Moeller, Dolf Weijers and R. Scott Poethig. (2009) Cyclophilin40 promotes the activity of ARGONAUTE1 in Arabidopsis. PNAS 106: 5424-5429.

16.Christine Hunter, Matthew Willmann, Gang Wu, M. Gutierrez-Nava and R. Scott. Poethig (2006) Trans-acting siRNA mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis. Development 133:2973-2981.

17.Ayoko Yamaguchi, Minnfeng Wu, Li Yang, Gang Wu, R. Scott Poethig, Doris Wagner (2009) The microRNA-reguated SBP-box transcription factor SPL3 is a direct transcriptional activator of LEAFY, FRUITFULL and APETALA1. Developmental Cell 17(2): 268-278.

18.Yi Li, Yi M. Bao, Chun H. Wei,Zhen S. Kang, Yong W. Zhong, Peng Mao, Gang Wu, Zhang L. Chen, Joachim Schiemann, and Richard S. Nelson (2004) Rice dwarf phytoreovirus segment S6-encoded nonstructural protein has a cell-to-cell movement function. Journal of Virology 78(10): 5382-5389.

    19. .Poethig, R. S., A. Peragine, M. Yoshikawa, C. Hunter, M. Willmann and G. Wu (2006) The function of RNAi in plant development. Cold Spring Harbor Symp. Quant. Biol. 71: 165-170.

 

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